Professor Lynn Corcoran
In 1975 I began my scientific career at the University of Melbourne. After a BSc(Hons) in Biochemistry, I undertook a PhD with Jerry Adams at the Walter and Eliza Hall Institute (WEHI), focussing on the oncogenic changes suffered by the c-myc locus in lymphoid tumours. After a first postdoc elucidating the genetics of the malaria parasite, with Dave Kemp, I went to the Whitehead Institute at MIT in Boston to work with David Baltimore. There I cloned lymphoid-specific transcription factors and made mouse knockouts of new genes identified by the Baltimore group. I returned to WEHI as a laboratory head in 1991, and continued studies on the transcriptional regulators that shape the adaptive immune system, mostly from the B cell perspective. The WEHI 'B cell Program' - formed in 2003 with Phil Hodgkin, Steve Nutt, David Tarlinton and myself - has enabled a systems approach to the regulation of antibody that continues to this day.
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